For over a thousand years before the arrival of European explorers, Sycamore Shoals and adjacent lands had been inhabited by Native Americans. The first permanent European settlers arrived in 1770, and established the Watauga Association— one of the first written constitutional governments west of the Appalachian Mountains— in 1772. Richard Henderson and Daniel Boone negotiated the Treaty of Sycamore Shoals in 1775, which saw the sale of millions of acres of Cherokee lands in Kentucky and Tennessee and led to the building of the Wilderness Road. During the American Revolution, Sycamore Shoals was both the site of Fort Watauga, where part of a Cherokee invasion was thwarted in 1776, and the mustering ground for the Overmountain Men in 1780
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